HLA-G–Presented Peptides: Defining a New Class of Neoantigen Targets for Hard-to-Treat Solid Tumours

  • Why HLA-G? Restricted expression in healthy tissues and enrichment in hypoxic, advanced tumours
  • Enabling technologies for high-confidence identification of HLA-G–bound peptide repertoires
  • Translational insights from mapping the HLA-G immunopeptidome in pancreatic ductal adenocarcinoma (PDAC)