Jon Moore
Chief Scientific Officer Epitopea Ltd
Dr Jon Moore is the Chief Scientific Officer and co-founder of Epitopea, and a biochemist and cell biologist with over 20 years of leadership experience in the biotech industry, primarily in oncology. He is also an Operating Partner at Advent Life Sciences, where he has helped found multiple companies, including Epitopea and Pheno Therapeutics. Previously, he served as CSO of Horizon Discovery and Head of Biology at Vernalis, leading drug discovery and early-stage research collaborations. He holds a PhD from the University of Newcastle and has extensive postdoctoral research experience in cancer biology.
Seminars
Thursday 23rd July 2026
Exploring Why We Need to Mine the Dark Genome to Find the Targets for Affordable Multi-valent Immunotherapies
9:00 am
- Exploring the limitations of conventional neoantigens including immune escape and restricted patient coverage
- How aberrantly expressed TSAs represent an untapped source of highly tumour specific targets that may evade central tolerance
- Demonstration of the potential of dark genome antigens for tumour control in mice & modelling performance of multi-valent off-the-shelf cancer vaccines in patients
