Thomas Böldicke
Senior Scientist Helmholtz Centre for Infection Research
Seminars
Thursday 23rd July 2026
T-Cell Memory, Tumor Microenvironment, and Alloreactivity in Intracellular Neoantigen–Targeted Immunotherapy
1:30 pm
- Emerging evidence highlights the importance of memory T-cell subsets, particularly stem-like and central memory populations, in sustaining long-term antitumor immunity.
- However, their function is frequently constrained by immunosuppressive cellular networks and metabolic barriers within the TME, including regulatory T cells, tumor-associated macrophages, and myeloid-derived suppressor cells.
- In parallel, advances in graft engineering and T-cell receptor editing provide strategies to mitigate alloreactivity while preserving graft-versus-tumor effects.
Wednesday 22nd July 2026
Chair’s Opening Remarks
7:50 am
Wednesday 22nd July 2026
Chair’s Closing Remarks
4:30 pm
